Gene clustering pattern, promoter architecture, and gene expression stability in eukaryotic genomes
نویسندگان
چکیده
منابع مشابه
Gene clustering pattern, promoter architecture, and gene expression stability in eukaryotic genomes.
A balance between gene expression stability and evolvability is essential for the long-term maintenance of a living system. In this paper, we studied whether the genetic and epigenetic properties of the promoter affect gene expression variability. We hypothesized that upstream distance and orientation (head-to-head or head-to-tail) are important for the promoter architecture and gene expression...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2011
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1100210108